Blar i forfatter "Rosenlund, Ingrid Arctander"

Viser treff 1-2 av 2

    • Experimental gene expression modulation - A practical and theoretical approach 

      Rosenlund, Ingrid Arctander (Master thesis; Mastergradsoppgave, 2019-06-03)
      The aim of this project was to create a stable knockout cell model with the CRISPR/Cas9 method for programmable genome editing that would make it possible to run long term assays to further investigate the cellular function of the long non-coding RNA FAM83H-AS1. The CRISPR/Cas9 method is compared to gene knockdown with small interfering RNAs (siRNAs) and short hairpin RNAs (shRNAs) via the RNA ...

    • The long noncoding RNA NEAT1 and nuclear paraspeckles are up-regulated by the transcription factor HSF1 in the heat shock response 

      Lellahi, Seyed Mohammad; Rosenlund, Ingrid Arctander; Hedberg, Annica; Kiær, Liv Torill; Mikkola, Ingvild; Knutsen, Erik; Perander, Maria (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-10)
      The long noncoding RNA (lncRNA) <i>NEAT1</i> (nuclear enriched abundant transcript 1) is the architectural component of nuclear paraspeckles, and it has recently gained considerable attention as it is abnormally expressed in pathological conditions such as cancer and neurodegenerative diseases. <i>NEAT1</i> and paraspeckle formation are increased in cells upon exposure to a variety of environmental ...